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Ivermectin, a potential anticancer drug derived from an …
Ivermectin has powerful antitumor effects, including the inhibition of proliferation, metastasis, and angiogenic activity, in a variety of cancer …
Ivermectin has New Application in Inhibiting Colorectal …
Colorectal cancer (CRC) is the third most common cancer worldwide and still lacks effective therapy. Ivermectin, an antiparasitic drug, has been shown …
Ivermectin has New Application in Inhibiting Colorectal …
Colorectal cancer (CRC) is the third most common cancer worldwide and still lacks effective therapy. Ivermectin, an antiparasitic drug, has been shown …
The multitargeted drug ivermectin: from an antiparasitic …
Ivermectin modifies the epigenetic signature and the self-renewal activity in the malignant cell due to its ability to mimic the SIN3-interaction that …
Ivermectin as an inhibitor of cancer stem‑like cells
The aim of the present study was to demonstrate that ivermectin preferentially inhibited cancer stem‑like cells (CSC) in breast cancer cells and …
Anti-parasite drug ivermectin can suppress ovarian cancer …
Ivermectin, as an old anti-parasite drug, can suppress almost completely the growth of various human cancers, including ovarian cancer (OC). However …
Anti-parasite drug ivermectin can suppress ovarian cancer …
Relevance: Ivermectin, as an old anti-parasite drug, can suppress almost completely the growth of various human cancers, including ovarian cancer …
Antitumor effects of ivermectin at clinically feasible …
Purpose: Ivermectin is an antiparasitic drug that exhibits antitumor effects in preclinical studies, and as such is currently being repositioned for c …
Antibiotic ivermectin preferentially targets renal cancer …
Renal cell carcinoma (RCC) is the most aggressive type of genitourinary cancer and highly resistant to current available therapies. In this work, we …
National Cancer Institute
Find technical definitions and synonyms by letter for drugs/agents used to treat patients with cancer or conditions related to cancer. Each entry …
Ivermectin: a systematic review from antiviral effects to …
Ivermectin proposes many potentials effects to treat a range of diseases, with its antimicrobial, antiviral, and anti-cancer properties as a wonder …
Ivermectin induces apoptosis of esophageal squamous cell …
Taken together, these data suggest that ivermectin inhibits the growth of esophageal cancer both in vitro and in vivo. It had been reported that iverm …
Ivermectin inactivates the kinase PAK1 and blocks the PAK1 …
Ivermectin is an old anti-parasitic antibiotic which selectively kills nematodes at a very low dose (0.2 mg/kg) by inhibiting their GABA …
Doxycycline, salinomycin, monensin and ivermectin …
Doxycycline, salinomycin, monensin and ivermectin repositioned as cancer drugs Bioorg Med Chem Lett. 2019 Jul 1;29(13):1549-1554. doi …
The river blindness drug Ivermectin and related …
Ivermectin inhibits lung cancer xenograft growthin vivo. Beyond colon cancer, WNT-TCF signaling has been implicated in a number of other tumor types …
National Cancer Institute
Frederick National Laboratory for Cancer Research . Bioinformatics, Big Data, and Cancer. Key Initiatives. Progress. Annual Report to the Nation …
Progress in Understanding the Molecular Mechanisms …
Ivermectin causes cell death in cancer cell lines by inducing PAK1-mediated cytostatic autophagy, caspase-dependent apoptosis and immunogenic cell …
Quercetin and cancer: new insights into its therapeutic …
Ovarian cancer is known as a serious malignancy that affects women’s reproductive tract and can considerably threat their health. A wide range of …
Ivermectin converts cold tumors hot and synergizes with …
We show that treatment with the FDA-approved anti-parasitic drug ivermectin induces immunogenic cancer cell death (ICD) and robust T cell infiltration …
Ivermectin inhibits canine mammary tumor growth by …
Ivermectin inhibited the proliferation of cancer cells (Fig. 1 a and b) with less effects on a normal canine epithelial cell line (Fig. 1 d), which …