As I come across interesting things about the Wuhan Flu, rather than adding new posts, I’ll just keep adding things to a coronavirus Plague page. New things on top.
My parents, who are in their 90s and living in a retirement residence, tested positive for the Wuhan Flu / Covid19. They are in generally good health for their age, physically, particularly my dad. First symptoms earlier this week. I’ll keep this updated as there are more developments.
Update 1: Pop’s doc, claiming studies linked chloroquine to kidney damage (no specifics given, but likely something like the crappy Brazilian or Swedish studies that used high doses of chloroquine, which is known to be toxic (and why we now use hydroxychloroquine instead)), refuses to proscribe HYDROXYchloroquine or z-pax or anything. He’s already taking a multi-vitamin and some extra D3, so they (pop, doc, my sister, who has power of attorney and is heavily involved in parental support and medical things) don’t think that any additional is needed on that front. Treatment plan is “monitor them, if symptoms worsen call 911 and go to the ER.” My dad, who gives great weight to professional / credentialed opinions, agrees. Sigh. Prayers and hopes that generally good underlying health will suffice. If not, I will not be amused.
Update 2: Latest report is that they are improving steadily. Mom in no discomfort, no more coughing, dad back to sounding grumpy rather than just tired and old. General health signs like blood oxygen and temp are good. Basically, a very minor case or strain of it, and good general health, appears to mean that even without any medication intervention things are generally looking good. Once they have recovered, presumably, because they can no longer catch it, they are likely to be out of lock / quarantine.. Continue reading Wuhan Flu in the family
I’ve seen a number of reports, news stories, and comments in various places that testing a treatment or cure for the Wuhan Flu / Covid19 would be horribly difficult and time consuming, saying in effect that because the fatality rate is so low – something less than 2% (possibly lower than 0.5% if there are a lot of asymptomatic cases out there) – that you’d have to test a HUGE number of people in order to prove the effectiveness, because in 98%+ of the cases people survive anyway. In a word, NO. Continue reading Testing low-rate problems
When life is happening fast, you have to respond fast. I find it interesting that Dr. Fouci (the CDC communicable disease guy on the podium supposedly advising Trump about the Wuhan virus) keeps dismissing the hydroxychloroquine + z-pak + zinc treatment / cure for the disease as “mere anecdote, not rigorous studies showing efficacy.” OK, fair enough. But he’s been saying that for WEEKS. It is claimed to have some effect in 12-24 hours, major improvement in 2-3 days, and perhaps clear it totally in 5. We are now adding more than 10,000 new cases a DAY. How long does it take to put together a study that could test a few thousand people when we’d literally know in a week if it works? I could design a study in a day that would have two or three variables, have a team assemble the med-packs by hand in a day while a couple of web-app geniuses put together a simple data-collection app/website, and in ten days we could have results of a control, five variations of meds, and six thousand or more participants in each treatment groups (control/placebo, hydroxychloroquine only + placebo, hydroxychloroquine + zinc, hydroxychloroquine + zpak, hydroxychloroquine + z-pak + zinc, hydroxychloroquine + z-pak + zinc + vitamins C and D3), somewhat blocked by sex, age, race, and health. Two weeks, tops. Why in the hell can’t these bozos do it in a month with all the money they have to spend?
The normal course of the disease is that it’s a pain for about ten days, then it either starts clearing up, or for about one in five of them it takes a turn for the worse; it’s at this point folk usually head for the ER or Urgent Care. Have them start taking it as soon as possible, then have everyone report their health status on a daily basis via the web-site. Each person would have basic stats and an approximate guess of how many days they’d been symptomatic when they started taking it. Everyone being tested gets a random treatment packet, and they can be blocked up with similar starting dates and demographics taking the other treatments later. You could gather a large enough dataset very quickly that data size would make up for imperfections in perfect blocking and randomization. Two weeks max you’d know conclusively the proper course. With 20% needing some sort of serious medical attention at around day ten, and most people likely starting their meds around day 5 on average, anything less than 10 % taking that turn would be HUGE. And considering the cost per dose on the whole package is ~$5, there isn’t any reason to not do it.
I’d bet they CAN…. so why don’t they? What do they gain by it? Why are they deliberately slow-walking the science? Whose team are they really on?
The following is a work of speculation. I have no specific data showing this is true. It is just a possible ‘what if” sort of story. If it pans out as true, well, some speculation is more astute than others. Continue reading Seeds of self-destruction
Got out of the house for a little while today, went to Costco. Outside was a queue, with good “social spacing” being reminded by the team of cart-wranglers who were sanitizing all the carts (particularly the push bar). They were letting people in in groups as people came out. Inside was not at all crowded – easy to keep spaced out, and 2/3 or maybe 3/4 of the people wore masks. Most of the employees didn’t. Continue reading Another shelf-report
In this video, Rudy Giuliani interviews Dr. Vladmir Zelenko about his Wuhan Flu treatment regimen. I’m not a big fan of Rudy’s interview style (to much prosecutor-like interruption), but good info. should be qued up to the start of things, the details of his dosage is at about the 30 minute mark.
Related note on the overall mortality rate:
WTF? Why is the overall mortality falling? That is potentially a HUGE question that needs a well-supported answer.
A really short one with the zinc tie-in.
In the last couple of days I’ve ordered a couple of different non-medical/food items from Amazon. One of them is now listed as “out for delivery” only a couple of days after ordering it (a better chair for my work-from-home situation). Another item shown as “in stock” is now says I should expect delivery near the end of April. A month or so. Huh. Interesting.
Other internet-only companies like NewEgg are shipping non-food items much faster, because they don’t have to prioritize groceries. Looking at current availability of items at other sites like Midway USA (guns and reloading supplies, mostly) is showing rather spotty inventory: looking at bullets, they have 800 items in stock, 748 out of stock with no backorder, and 714 “temporarily unavailable.” I don’t think I’ve ever seen the orderable : not-orderable ratio anywhere near that skewed. IIRC, it’s typically more like 3:1 rather than 1:3. On Ammo they have 694 types “available,” and 1006 as “out of stock no backorder” or “temporarily unavailable,” a 7:10 ratio. Highest I’ve seen it since, I think, the gun-run of Obama’s re-election panic.
OTOH, the news on cures/treatments for the Wuhan Flu continues to be good with respect to various combinations of hydroxychloroquine + other meds, so things should be returning to normal relatively soon.
I stopped in at a Fred Meyer (PNW chain) to pick up a few things on the way home from my sister’s place Sunday afternoon. Paper products and cleaning supplies had a lot of empty shelf space, but they were not totally out of TP. They were pretty low on some staples like eggs and milk. LOADS (numerous pallets filled in the display aisle places) of bottled water. Parking lot was less full than I expected. They had a Purel wipe dispenser by the shopping carts so you could wipe it down before use – it’s possible that it isn’t a new item and is just getting a lot more notice and use these days, it’s not a specific store I normally visit. Corona Beer was on sale. People were generally keeping reasonable distances apart.
One thing I noticed on the drive was that a lot of places were still open, contrary to expectations. Car dealerships. Espresso stands. Marijuana shops. I expected gas stations and grocery stores and restaurants (to-go only), but not an auto-parts store or oil-change place. Be interesting to know what percentage of business are claiming to be “critical infrastructure” and just being “really careful.”
One of the puzzling things about Covid-19 has been filtering through the reporting of various reports -economic, medical, political, etc.- trying to get a proper understanding of what the risks really are. But even evaluating the actual medical risks based on reported death rates has been nearly impossible to make sense of until I came across an article that reminded me of a common complicating factor in understanding gun/murder stats. Continue reading “With” versus “from”